Lead-212 is a promising radionuclide for cancer therapy, but no primary 212Pb activity standardization has been published. A need therefore exists for accurate estimation of injected doses of 212Pb activity in equilibrium with progeny, when it comes to preclinical and clinical trials. In this study, 212Pb activity was determined using a high purity germanium (HPGe) detector, which allowed the determination of geometry-specific calibration factors for commercially available reentrant ionization chambers (ICs) and sodium iodide (NaI) detectors.In this work, 960 réis coins from the period when Brazil was a colony of Portugal were analyzed using the x-ray fluorescence (XRF) spectrometry. The history of these coins, dated between the end of the 17th century and the beginning of the 19th century, had a great influence on the immigration of the Portuguese Prince Regent D. João to Brazil, who arrived in 1808. Bearing in mind the need to expand the timid Brazilian monetary system, the Portuguese crown decided to collect Spanish silver pesos of 8 reales, recoined with a value of 960 réis. The recoinage procedure was carried out using a stamp; therefore, in many cases, it is possible to check the base currency. In this work, were investigated 17 samples of 960 réis coins by XRF, in which the base coin was 8 reales manufactured with raw materials from Mexican mines. In addition to characterizing the elemental composition of the coins, the XRF data were evaluated using multivariate statistical method of Robust Principal Component Analysis (ROBPCA), which was used to classify the coins based on their elemental composition. However, with XRF, elementary information is obtained for a depth of only a few micrometers. One of the essential issues in Ag-Cu metal alloys is the Ag enrichment, which can cause changes to the elemental composition of the surface. Therefore, initially, a study was carried out to verify whether the surface compositions of the coins were altered by the Ag enrichment.186gRe (T1/2?=?3.7183?d, E(β-)mean?=?346.7?keV, I(β-)mean?=?92.59%), a mixed beta and γ-emitter shows great potential for use in theranostic applications. The dominant 185Re(n,γ) route, via use of a nuclear reactor, provides 186gRe in carrier added form with low specific activity, while cyclotrons offer no carrier-added (NCA) high specific activity production of 186gRe. However, to be able to select the best possible nuclear reaction and to optimize the production route via the use of a cyclotron, information on the excitation function for the reaction of interest as well as for the competing reactions is necessary. Accordingly, we have conducted a detailed study of the excitation functions for natW(d, x) reactions in seeking optimized parameters for the NCA production of 186gRe. Noting a discrepancy among the experimental data, we made an evaluation of the available literature, finally selecting optimum parameters for the production of 186gRe via the 186W(d,2n)186Re reaction. These beam parameters were then used for batch production of 186gRe by irradiating an enriched 186W metallic powder target, followed by a subsequent automated chemical separation process. The preliminary results show 98.1% radionuclidic purity of 186gRe at 8?h subsequent to the End of Bombardment (EOB), offering the potential for use in clinical applications.The analytical formulas of the surface emitted energy spectra of an alpha infinite flat source are derived, using the derived formulas of the distribution of residual range of alpha particles, considering the different thicknesses of the source and the absorbing layer. Utilizing these formulas, the typical residual range distributions and the energy spectra of alpha particles have been calculated and shown in figures. The variation tendency of the calculated spectrum is in good agreement with the measured spectrum.Investigation of neutron-induced background was carried out by studying interactions of cosmic-ray neutrons with an HPGe detector inside its shield placed on a ground floor of a 3-storey building. The study was conducted experimentally and by Monte Carlo simulations using GEANT4 simulation tool. Detailed analysis of measured background γ-ray spectra showed that many γ-lines visible in the spectra were induced by neutrons. The majority of detected γ-rays originated in germanium, copper, lead and tin. Iron and aluminium components were less important background sources. Inelastic scattering and neutron capture were the most often occurring processes of neutron interactions with the detector and its shielding. https://www.selleckchem.com/products/azd9291.html The contamination by natural radionuclides, specifically of 40K, 214Pb, 214Bi and 208Tl, was also present in the background spectra. Nevertheless, approximately 35% of 208Tl peak at the energy of 2614.51 keV was produced by inelastic scattering of neutrons on 208Pb nuclei. The experimental background was compared with GEANT4 simulations, which were carried out without and with the shielding layer of the building. The final integral counting rates for measured spectrum in the energy range from 50 keV to 2875 keV was 1.26 ± 0.07 s-1 and for simulated one 1.25 ± 0.13 s-1, indicating very good agreement with the experiment.Present study investigated the Cu2+ removal potential of Trichoderma lixii CR700, isolated from enormously heavy metal polluted electroplating wastewater. In the batch study, actively growing CR700 was able to remove 84.6% of Cu2+ at the concentration 10 mg/L of Cu2+ within 120 h after incubation and the accumulated and surface adsorbed amount of Cu was 0.51 and 0.47 mg/g of dry biomass respectively. T. lixii CR700 also showed efficient Cu2+ removal potential in the pH ranges from 5.0 to 8.0, in the presence of other co-occurring contaminant such as heavy metal, anions and metabolic inhibitor as well from real tannery wastewater. Alteration on cell surface of Cu2+ treated mycelia of T. lixii CR700 was analyzed using scanning electron microscope. Fourier transform infrared spectroscopic analysis was performed to identify the role of surface functional group in Cu2+ adsorption which revealed that COO─ functional group lead Cu2+ adsorption onto the surface of T. lixii CR700. Thus, T. lixii CR700 uses simultaneous surface sorption and accumulation mechanism in Cu2+ removal and can be potentially applied for bioremediation of Cu2+ contaminated wastewater in ecofriendly, safe and sustainable way.